Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28527012 | 0.84 | HTR2A (0.40) | HTR2AHTR2CHTR2BHTR1AHTR7 | |
| SCHEMBL28520458 | 0.77 | CYP2D6 (0.41) | GPR84SLC6A4 | |
| SCHEMBL28783300 | 0.73 | KDM4E (0.40) | SLC6A4 | |
| SCHEMBL28528721 | 0.73 | GPR84 (0.41) | GPR84SLC6A4HTR2AALKBH5FTO | |
| SCHEMBL28524815 | 0.68 | DYRK1A (0.39) | SLC6A4 | |
| SCHEMBL28519480 | 0.66 | HTR2A (0.42) | HTR2AFTOHTR6 | |
| SCHEMBL6640448 | 0.64 | SLC6A4 (0.52) | FFAR1GPR84SLC6A4HTR2AHTR2C | |
| SCHEMBL27779713 | 0.64 | SLC6A4 (0.59) | FFAR1GPR84SLC6A4HTR2AHTR2C | |
| SCHEMBL12120939 | 0.64 | GPR84 (0.58) | FFAR1GPR84SLC6A4HTR2AHTR2C | |
| SCHEMBL19104226 | 0.63 | GPR84 (0.53) | FFAR1GPR84SLC6A4HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912579-B | Preparation method of 2, 2-disubstituted tetrahydrofuran derivative | 华中科技大学 | 2021-01-08 | — | — | CN | disclosed |