SCHEMBL28520102

SCHEMBL28520102

CCC/C=C/C#CC=C(OCCCC)OCCCC

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.40
HCAR2 Q8TDS4 3/20 0.40
PPARG P37231 1/20 0.39
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
ALDH1A1 P00352 1/20 0.34
HMGCR P04035 4/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
FAAH O00519 1/20 0.31
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28531521 1.00 ATM (0.40) ATMHCAR2PPARGHPGDTSHR
SCHEMBL28532519 0.95 HCAR2 (0.41) ATMHCAR2PPARGHPGDTSHR
SCHEMBL28531584 0.95 HCAR2 (0.41) ATMHCAR2PPARGHPGDTSHR
SCHEMBL28525874 0.93 HCAR2 (0.42) ATMHCAR2PPARGTSHRHMGCR
SCHEMBL29156588 0.93 HCAR2 (0.42) ATMHCAR2PPARGTSHRHMGCR
SCHEMBL28523639 0.93 HCAR2 (0.42) ATMHCAR2PPARGTSHRHMGCR
SCHEMBL28907550 0.93 HCAR2 (0.42) ATMHCAR2PPARGTSHRHMGCR
SCHEMBL28531890 0.92 HMGCR (0.40) ATMHPGDTSHRHMGCRFAAH
SCHEMBL28531520 0.92 HMGCR (0.40) ATMHPGDTSHRHMGCRFAAH
SCHEMBL28524445 0.89 PPARG (0.37) HCAR2PPARGFAAHCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112441895-A Dialkoxyl alkadienyne compound, preparation method thereof and preparation method of diene alkynal compound 信越化学工业株式会社 2021-03-05 CN disclosed