Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SQLE | Q14534 | 3/20 | 0.31 |
| ▸ | LSS | P48449 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 3/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844669 | 0.78 | PTPN1 (0.32) | PTPN1ALDH1A1ALOX15 | |
| SCHEMBL9844659 | 0.78 | ALDH1A1 (0.59) | PTPN1ALDH1A1ALOX15FNTAPGGT1B | |
| SCHEMBL2864565 | 0.77 | PTPN1 (0.33) | PTPN1ALDH1A1ALOX15SQLELSS | |
| SCHEMBL2864562 | 0.77 | PTPN1 (0.33) | PTPN1ALDH1A1ALOX15SQLELSS | |
| SCHEMBL7460979 | 0.77 | — | — | |
| SCHEMBL7460989 | 0.77 | — | — | |
| SCHEMBL21518297 | 0.75 | FNTA (0.37) | PTPN1ALDH1A1ALOX15LSSFNTA | |
| SCHEMBL21518291 | 0.75 | FNTA (0.37) | PTPN1ALDH1A1ALOX15LSSFNTA | |
| SCHEMBL28508970 | 0.75 | — | — | |
| SCHEMBL9844681 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530241-B | Preparation method of benzo ring derivative with benzyl quaternary carbon center | 武汉大学 | 2021-02-02 | — | — | CN | disclosed |