Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.61 |
| ▸ | CNR2 | P34972 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 3/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28520169 | 1.00 | CNR1 (0.61) | CNR1CNR2L3MBTL1HTR1ADRD2 | |
| SCHEMBL28528627 | 1.00 | CNR1 (0.61) | CNR1CNR2L3MBTL1HTR1ADRD2 | |
| SCHEMBL28528626 | 1.00 | CNR1 (0.61) | CNR1CNR2L3MBTL1HTR1ADRD2 | |
| SCHEMBL28519578 | 0.98 | HTR1A (0.60) | CNR1CNR2L3MBTL1HTR1ADRD2 | |
| SCHEMBL28527312 | 0.98 | HTR1A (0.60) | CNR1CNR2L3MBTL1HTR1ADRD2 | |
| SCHEMBL28530081 | 0.92 | TSHR (0.55) | CNR1CNR2L3MBTL1HTR1ADRD2 | |
| SCHEMBL28907245 | 0.91 | HTR1A (0.67) | L3MBTL1HTR1ADRD2TSHRMEN1 | |
| SCHEMBL28523079 | 0.91 | HTR1A (0.67) | L3MBTL1HTR1ADRD2TSHRMEN1 | |
| SCHEMBL9565884 | 0.86 | CNR1 (0.66) | CNR1CNR2TSHRMEN1LMNA | |
| SCHEMBL9565882 | 0.86 | CNR1 (0.66) | CNR1CNR2TSHRMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041291-B | Macamide derivative and preparation method thereof | 北京采瑞医药科技研究院有限公司 | 2021-02-26 | — | — | CN | disclosed |