Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.61 |
| ▸ | ESRRG | P62508 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALPL | P05186 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28511901 | 0.90 | DNM1 (0.58) | DNM1ESRRGMAPTGAAHTT | |
| SCHEMBL28519771 | 0.89 | CA12 (0.58) | ESRRGMAPTGAAALDH1A1TP53 | |
| SCHEMBL23230120 | 0.89 | MAPT (0.64) | ESRRGMAPTGAAHTTALDH1A1 | |
| SCHEMBL16035566 | 0.87 | DUSP3 (0.69) | DNM1ESRRGMAPTGAAHTT | |
| SCHEMBL16035565 | 0.87 | DUSP3 (0.69) | DNM1ESRRGMAPTGAAHTT | |
| SCHEMBL12858673 | 0.87 | DUSP3 (0.69) | DNM1ESRRGMAPTGAAHTT | |
| SCHEMBL28516030 | 0.87 | GAA (0.73) | MAPTGAAHTTALDH1A1POLB | |
| SCHEMBL21887103 | 0.85 | ESRRG (0.64) | ESRRGMAPTGAAHTTALDH1A1 | |
| SCHEMBL23698301 | 0.85 | ESRRG (0.64) | ESRRGMAPTGAAHTTALDH1A1 | |
| SCHEMBL13186578 | 0.83 | ESRRG (0.79) | DNM1ESRRGGAAPOLBNOX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112079744-A | Aromatic acylhydrazone derivatives and application thereof as NA (adenosine) inhibitor | 湖南大学 | 2020-12-15 | — | — | CN | claimed |
| CN-112079744-B | Aromatic acylhydrazone derivatives and application thereof as NA (adenosine) inhibitor | 湖南大学 | 2021-07-30 | — | — | CN | disclosed |
| CN-112079744-A | Aromatic acylhydrazone derivatives and application thereof as NA (adenosine) inhibitor | 湖南大学 | 2020-12-15 | — | — | CN | disclosed |