Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274777 | 0.81 | MAP3K14 (0.44) | MAP3K14GLACRBNDDB1CYP19A1 | |
| SCHEMBL17907172 | 0.80 | MAP3K14 (0.48) | MAP3K14GLACRBNDDB1CYP19A1 | |
| SCHEMBL1838214 | 0.79 | MAP3K14 (0.43) | MAP3K14GLACRBNDDB1CYP19A1 | |
| SCHEMBL1056468 | 0.79 | MAP3K14 (0.43) | MAP3K14GLACRBNDDB1CYP19A1 | |
| SCHEMBL1536267 | 0.79 | MAP3K14 (0.43) | MAP3K14GLACRBNDDB1CYP19A1 | |
| SCHEMBL23199745 | 0.79 | MAP3K14 (0.43) | MAP3K14GLACRBNDDB1CYP19A1 | |
| SCHEMBL10573688 | 0.78 | — | — | |
| SCHEMBL18909611 | 0.76 | — | — | |
| SCHEMBL19839455 | 0.76 | — | — | |
| SCHEMBL13378339 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112088168-A | Chemoselective thiol coupling with alkene-or alkyne-thiophosphonates and-phosphonates | 柏林合作研究学会 | 2020-12-15 | — | — | CN | disclosed |