Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | QDPR | P09417 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3359855 | 0.97 | — | — | |
| SCHEMBL4556181 | 0.97 | GPR119 (0.43) | GPR119NCF1LMNACYP2C9TSHR | |
| SCHEMBL7928 | 0.97 | — | — | |
| Methane SCHEMBL2671466 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL6489107 | 0.94 | — | — | |
| Ethane SCHEMBL27516222 | 0.94 | GPR119 (0.42) | GPR119NCF1LMNACYP2C9TSHR | |
| Hno SCHEMBL27257994 | 0.88 | GPR119 (0.39) | GPR119NCF1LMNACYP2C9TSHR | |
| SCHEMBL23107536 | 0.86 | — | — | |
| SCHEMBL19045196 | 0.86 | — | — | |
| SCHEMBL2487331 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218845-A | FOXM1 inhibitor compositions and methods of use thereof | 伊利诺伊大学理事会 | 2021-01-12 | — | — | CN | claimed |
| CN-112218845-A | FOXM1 inhibitor compositions and methods of use thereof | 伊利诺伊大学理事会 | 2021-01-12 | — | — | CN | disclosed |