Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.36 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.36 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.36 |
| ▸ | STIM2 | Q9P246 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852314 | 0.94 | CCR1 (0.44) | CCR1MAPTLPAR1RIPK1GPR6 | |
| SCHEMBL2857074 | 0.89 | LPAR1 (0.42) | CCR1MAPTLPAR1GPR6SMN1; SMN2 | |
| SCHEMBL2858515 | 0.87 | MAPT (0.44) | CCR1MAPTRIPK1GPR6SMN1; SMN2 | |
| SCHEMBL2857241 | 0.85 | MAPT (0.44) | CCR1MAPTGPR6SMN1; SMN2POLB | |
| SCHEMBL2859102 | 0.84 | MAPT (0.45) | MAPTSMN1; SMN2TRPC1TRPC3STIM1 | |
| SCHEMBL2850694 | 0.83 | MAPT (0.41) | CCR1MAPTGPR6SMN1; SMN2POLB | |
| SCHEMBL2852244 | 0.82 | MAPT (0.48) | MAPTGPR6SMN1; SMN2POLBTRPC1 | |
| SCHEMBL2858283 | 0.82 | MAPT (0.43) | CCR1MAPTGPR6SMN1; SMN2POLB | |
| SCHEMBL2856949 | 0.82 | LPAR1 (0.48) | CCR1MAPTLPAR1SMN1; SMN2POLB | |
| SCHEMBL2860489 | 0.82 | RXFP1 (0.45) | CCR1MAPTSMN1; SMN2POLBNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |