Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29264942 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL15984634 | 0.85 | MAPT (0.54) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL16333816 | 0.85 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AMAPTBACE1 | |
| SCHEMBL16333817 | 0.85 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AMAPTBACE1 | |
| SCHEMBL15952707 | 0.84 | MAPT (0.53) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL187778 | 0.84 | MAPT (0.53) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL15952706 | 0.84 | MAPT (0.53) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL187779 | 0.84 | MAPT (0.53) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL158285 | 0.83 | MAPT (0.68) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL10320671 | 0.83 | MAPT (0.68) | ALDH1A1MEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221577-A | 2-Phenoxyquinoline derivative, and preparation method and application thereof | 湖南中医药大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-111808031-B | Ferulic acid derivative and preparation method and application thereof | 湖南中医药大学 | 2022-01-14 | — | — | CN | disclosed |
| CN-111808031-A | Ferulic acid derivative and preparation method and application thereof | 湖南中医药大学 | 2020-10-23 | — | — | CN | disclosed |