Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 10/20 | 0.51 |
| ▸ | CA9 | Q16790 | 10/20 | 0.51 |
| ▸ | CA1 | P00915 | 6/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28509793 | 0.95 | CA12 (0.49) | CA12CA9CA1TUBB4ATUBB | |
| SCHEMBL28507801 | 0.94 | CA12 (0.52) | CA12CA9CA1TUBB4ATUBB | |
| SCHEMBL28512432 | 0.94 | CA12 (0.51) | CA12CA9CA1TUBB4ATUBB | |
| SCHEMBL28907118 | 0.93 | CA12 (0.56) | CA12CA9CA1TUBB4ATUBB | |
| SCHEMBL28521298 | 0.93 | CA12 (0.55) | CA12CA9CA1TUBB4ATUBB | |
| SCHEMBL28507798 | 0.93 | CA12 (0.53) | CA12CA9CA1TUBB4ATUBB | |
| SCHEMBL28521376 | 0.92 | CA12 (0.50) | CA12CA9CA1TUBB4ATUBB | |
| SCHEMBL28512425 | 0.91 | TUBB4A (0.49) | CA12CA9CA1TUBB4ATUBB | |
| SCHEMBL28519013 | 0.90 | CA12 (0.50) | CA12CA9CA1TUBB4ATUBB | |
| SCHEMBL28515764 | 0.89 | CA12 (0.57) | CA12CA9CA1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761964-B | Coumarin-3-hydroxypyridine-4-one derivative, and preparation method and application thereof | 浙江工业大学 | 2021-02-02 | — | — | CN | disclosed |