Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 3/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 4/20 | 0.31 |
| ▸ | CTSK | P43235 | 4/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28520996 | 0.89 | AAK1 (0.34) | ATMKLK5PPARAPPARGAAK1 | |
| SCHEMBL18427985 | 0.89 | ATM (0.39) | ATMKLK5APPAAK1LMNA | |
| SCHEMBL28521303 | 0.88 | PPARG (0.34) | ATMKLK5PPARAPPARGAAK1 | |
| SCHEMBL28527894 | 0.85 | ATM (0.37) | ATMKLK5APPSYKCACNA1B | |
| SCHEMBL28520977 | 0.83 | CTSS (0.36) | ATMKLK5SYKCACNA1BCTSS | |
| SCHEMBL28511521 | 0.82 | ATM (0.38) | ATMKLK5APPPSEN1PSEN2 | |
| SCHEMBL28521367 | 0.81 | ATM (0.36) | ATMKLK5AAK1LMNACACNA1B | |
| SCHEMBL28520988 | 0.80 | IDO1 (0.36) | ATMKLK5AAK1SYKLMNA | |
| SCHEMBL28514878 | 0.80 | IDO1 (0.36) | ATMKLK5AAK1LMNAACE | |
| SCHEMBL28520992 | 0.80 | IDO1 (0.36) | ATMKLK5AAK1SYKLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026026-B | Beta-substituted beta-amino acids and analogs as chemotherapeutic agents and uses thereof | 夸德里加生物科学公司 | 2021-02-09 | — | — | CN | disclosed |