Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27514767 | 0.89 | GAA (0.38) | ELANETP53LTA4HLMNACYP3A4 | |
| SCHEMBL16158023 | 0.84 | GAA (0.39) | ELANELMNATSHRKDM4EALDH1A1 | |
| SCHEMBL4017179 | 0.80 | ELANE (0.40) | ELANETP53LMNAKDM4EALDH1A1 | |
| SCHEMBL11147727 | 0.73 | NPC1 (0.41) | TP53LTA4HTSHRPLA2G2AGAA | |
| SCHEMBL4015672 | 0.71 | ELANE (0.40) | ELANELMNAKDM4EALDH1A1POLB | |
| SCHEMBL19172867 | 0.71 | PSEN1 (0.38) | TP53LMNAGPR84TSHRPLA2G2A | |
| SCHEMBL19232223 | 0.71 | THRB (0.38) | LMNATSHRTHRATHRB | |
| SCHEMBL12871708 | 0.69 | ELANE (0.36) | ELANELMNATSHRKDM4EALDH1A1 | |
| SCHEMBL11121933 | 0.68 | TSHR (0.42) | TP53LTA4HCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20471498 | 0.68 | PTPN1 (0.40) | TP53LTA4HLMNACYP3A4GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112390727-B | Oxime carboxylate compound and application thereof | 沈阳中化农药化工研发有限公司 | 2021-12-07 | — | — | CN | disclosed |
| CN-112390725-B | Preparation method of amide compound | 沈阳中化农药化工研发有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-112390727-A | Oxime carboxylate compound and application thereof | 沈阳中化农药化工研发有限公司 | 2021-02-23 | — | — | CN | disclosed |
| CN-112390725-A | Preparation method of amide compound | 沈阳中化农药化工研发有限公司 | 2021-02-23 | — | — | CN | disclosed |