Phenol

Phenol

SCHEMBL28522189

CN.COc1ccc(O)c2ccccc12.Oc1ccccc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.52
EP300 Q09472 3/20 0.50
KAT8 Q9H7Z6 2/20 0.50
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
CAPN1 P07384 1/20 0.44
CTSL P07711 1/20 0.44
CTSB P07858 1/20 0.44
CDC25B P30305 2/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
IMPDH2 P12268 1/20 0.43
IMPDH1 P20839 1/20 0.43
CETP P11597 1/20 0.43
HSP90AA1 P07900 1/20 0.43
PLK1 P53350 1/20 0.42
HDAC3 O15379 1/20 0.42
KAT2B Q92831 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroquinone SCHEMBL19873349 0.91 IDO1 (0.52) IDO1EP300KAT8ESR1ESR2
SCHEMBL217255 0.89 IDO1 (0.59) IDO1EP300KAT8ESR1ESR2
Methyl Alcohol SCHEMBL27974596 0.87 IDO1 (0.56) IDO1EP300KAT8ESR1ESR2
Acetic Acid SCHEMBL9812658 0.84 ESR1 (0.54) IDO1EP300KAT8ESR1ESR2
SCHEMBL28522186 0.81 IDO1 (0.47) IDO1EP300KAT8ESR1ESR2
SCHEMBL13265602 0.80 ESR1 (0.54) IDO1EP300KAT8ESR1ESR2
1-Naphthol SCHEMBL8587451 0.79 CYP1A2 (0.61) IDO1EP300KAT8ESR1ESR2
SCHEMBL3171781 0.77 MAPT (0.64) IDO1EP300ESR1ESR2CA1
SCHEMBL30312309 0.77 MAPT (0.64) IDO1EP300ESR1ESR2CA1
SCHEMBL29380721 0.76 IDO1 (0.73) IDO1EP300KAT8CDC25BCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107001828-B Radiation curable compositions 爱克发有限公司 2021-03-09 CN disclosed