1-Naphthol

1-Naphthol

SCHEMBL8587451

COc1ccc(O)c2ccccc12.Oc1cccc2ccccc12

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.61
CETP P11597 1/20 0.54
ESR1 P03372 2/20 0.53
ESR2 Q92731 2/20 0.53
MAPT P10636 3/20 0.52
NQO1 P15559 1/20 0.50
TP53 P04637 2/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
TSHR P16473 1/20 0.48
GAA P10253 2/20 0.47
IDO1 P14902 3/20 0.47
ALDH1A1 P00352 2/20 0.47
CYP3A4 P08684 2/20 0.47
HSD17B10 Q99714 2/20 0.47
KDM4E B2RXH2 2/20 0.47
HPGD P15428 2/20 0.47
LMNA P02545 1/20 0.47
ALOX15 P16050 1/20 0.47
ALOX12 P18054 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL217255 0.89 IDO1 (0.59) ESR1ESR2MAPTNQO1TP53
Methyl Alcohol SCHEMBL27974596 0.87 IDO1 (0.56) CETPESR1ESR2MAPTNQO1
SCHEMBL3171781 0.85 MAPT (0.64) ESR1ESR2MAPTTP53CA1
SCHEMBL30312309 0.85 MAPT (0.64) ESR1ESR2MAPTTP53CA1
SCHEMBL13265602 0.84 ESR1 (0.54) CETPESR1ESR2MAPTTP53
SCHEMBL5533274 0.83 PPARG (0.50) CYP1A2CETPESR1ESR2MAPT
Hydroquinone SCHEMBL19873349 0.83 IDO1 (0.52) ESR1ESR2MAPTNQO1TP53
1-Naphthol SCHEMBL558316 0.82 CYP1A2 (0.81) CYP1A2CETPESR1ESR2MAPT
SCHEMBL21619219 0.82 MAPT (0.49) CYP1A2CETPMAPTNQO1GAA
1-Naphthol SCHEMBL8904232 0.80 CYP1A2 (0.94) CYP1A2ESR1ESR2MAPTCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0455905-B1 Dipsticks for nucleic acid hybridization assays and methods for covalently immobilizing oligonucleotides MICROPROBE CORP (US) 1998-06-17 EP disclosed
US-5667976-A AMINE POLYMER COATING BECTON DICKINSON AND COMPANY (US) 1997-09-16 US disclosed
EP-0745689-A2 A dipstick for a nucleic acid hybridization assay MICROPROBE CORPORATION (US) 1996-12-04 EP disclosed
US-5514785-A POLYMER COATED BEAD FOR COVALENT IMMOBILIZATION OF OLIGONUCLEOTIDES; DIPSTICKS BECTON DICKINSON AND COMPANY (US) 1996-05-07 US disclosed
WO-1994000600-A1 SOLID SUPPORTS FOR NUCLEIC ACID HYBRIDIZATION ASSAYS MICROPROBE CORPORATION (US) 1994-01-06 WO disclosed
EP-0455905-A2 Solid supports for nucleic acid hybridization assays and methods for covalently immobilizing oligonucleotides MICROPROBE CORPORATION (US) 1991-11-13 EP disclosed