Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28523151 | 0.88 | MAPT (0.55) | POLBMAPTGAATP53KMT2A | |
| SCHEMBL28531020 | 0.84 | MAPT (0.51) | POLBMAPTGAAMAOBKMT2A | |
| SCHEMBL5112169 | 0.84 | POLB (0.50) | POLBKMT2AKIF11CA12CA1 | |
| SCHEMBL28516843 | 0.82 | GAA (0.60) | MAPTGAATP53KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5773679 | 0.82 | POLB (0.49) | POLBKMT2AKIF11CA12CA1 | |
| SCHEMBL28516840 | 0.81 | MAPT (0.56) | POLBMAPTGAAMAOBKMT2A | |
| SCHEMBL28523007 | 0.81 | KMT2A (0.59) | MAPTGAATP53KMT2ASMN1; SMN2 | |
| SCHEMBL11665506 | 0.81 | CYP1A1 (0.48) | MAPTGAACYP1A1CYP1B1MAOB | |
| SCHEMBL9779998 | 0.78 | MAPT (0.59) | POLBMAPTGAATP53KMT2A | |
| SCHEMBL28528087 | 0.77 | TP53 (0.52) | MAPTGAATP53KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279743-B | Synthesis method of chiral alpha-amino acid ester derivative | 中国科学院大连化学物理研究所 | 2022-10-18 | — | — | CN | disclosed |
| CN-112279743-A | Synthesis method of chiral alpha-amino acid ester derivative | 中国科学院大连化学物理研究所 | 2021-01-29 | — | — | CN | disclosed |