Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28516843 | 0.94 | GAA (0.60) | MAPTGAAALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28531020 | 0.92 | MAPT (0.51) | MAPTGAAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28516840 | 0.92 | MAPT (0.56) | MAPTGAAALDH1A1HTTLMNA | |
| SCHEMBL28523007 | 0.92 | KMT2A (0.59) | MAPTGAAALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9779998 | 0.89 | MAPT (0.59) | MAPTGAAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28522683 | 0.88 | POLB (0.49) | MAPTGAASMN1; SMN2KMT2ACA12 | |
| SCHEMBL28528087 | 0.88 | TP53 (0.52) | MAPTGAAALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL5122021 | 0.87 | MAPT (0.57) | MAPTGAAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28522877 | 0.85 | PPARG (0.56) | MAPTALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL28530760 | 0.84 | MAPT (0.50) | MAPTGAAALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279743-B | Synthesis method of chiral alpha-amino acid ester derivative | 中国科学院大连化学物理研究所 | 2022-10-18 | — | — | CN | disclosed |
| CN-112279743-A | Synthesis method of chiral alpha-amino acid ester derivative | 中国科学院大连化学物理研究所 | 2021-01-29 | — | — | CN | disclosed |