Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 5/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.42 |
| ▸ | GRM5 | P41594 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30302490 | 0.92 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CGRM5HTR2A | |
| SCHEMBL3948096 | 0.92 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CGRM5HTR2A | |
| Boric Acid SCHEMBL28522511 | 0.89 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CGRM5HTR2A | |
| SCHEMBL2301675 | 0.88 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CGRM5HTR2A | |
| SCHEMBL30484407 | 0.88 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CGRM5HTR2A | |
| SCHEMBL930529 | 0.86 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CGRM5HTR2A | |
| SCHEMBL21468769 | 0.79 | HTR2C (0.50) | ADRA2AADRA2BADRA2CHTR2AHTR2C | |
| SCHEMBL3162510 | 0.71 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CHTR2AHTR2C | |
| SCHEMBL31184295 | 0.71 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CHTR2AHTR2C | |
| SCHEMBL31587209 | 0.71 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521419-A | Method for preparing chiral nitrogen-phosphorus ligand L-8 containing pyridocyclopentane | 南京艾普特生物医药有限公司 | 2021-03-19 | — | — | CN | claimed |
| CN-112521420-A | Method for synthesizing chiral nitrogen and phosphorus ligand L-8 containing pyridocycloheptane | 南京艾普特生物医药有限公司 | 2021-03-19 | — | — | CN | claimed |
| CN-112375101-A | Method for preparing chiral nitrogen-phosphorus ligand L-8 containing pyridocyclohexane | 南京艾普特生物医药有限公司 | 2021-02-19 | — | — | CN | claimed |
| CN-112521419-A | Method for preparing chiral nitrogen-phosphorus ligand L-8 containing pyridocyclopentane | 南京艾普特生物医药有限公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-112521420-A | Method for synthesizing chiral nitrogen and phosphorus ligand L-8 containing pyridocycloheptane | 南京艾普特生物医药有限公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-112375101-A | Method for preparing chiral nitrogen-phosphorus ligand L-8 containing pyridocyclohexane | 南京艾普特生物医药有限公司 | 2021-02-19 | — | — | CN | disclosed |