Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24974730 | 0.83 | SLC2A1 (0.47) | SLC2A1SLC6A4SLC6A2AOC3CA12 | |
| SCHEMBL14593916 | 0.78 | SLC2A1 (0.53) | SLC2A1SLC6A4SLC6A2AOC3CA12 | |
| SCHEMBL17271883 | 0.75 | HTT (0.47) | SLC6A4SLC6A2CYP2C9TSHRAOC3 | |
| SCHEMBL12493468 | 0.75 | SLC6A2 (0.56) | SLC2A1SLC6A4SLC6A2TP53MAPT | |
| SCHEMBL28986653 | 0.75 | NPC1 (0.45) | SLC2A1SLC6A4SLC6A2CA1CA2 | |
| SCHEMBL8915315 | 0.73 | LDHA (0.47) | SLC2A1SLC6A4SLC6A2CYP2C9TSHR | |
| SCHEMBL9671113 | 0.73 | AOC3 (0.56) | SLC6A4SLC6A2AOC3SMN1; SMN2TAAR1 | |
| SCHEMBL6325694 | 0.71 | MEN1 (0.57) | — | |
| SCHEMBL6325691 | 0.71 | MEN1 (0.57) | — | |
| SCHEMBL23160468 | 0.70 | AOC3 (0.49) | SLC2A1SLC6A4SLC6A2AOC3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735400-B | Cyclic sulfamoyl arylamide derivatives and their use as medicaments for the treatment of hepatitis B | 爱尔兰詹森科学公司 | 2021-02-02 | — | — | CN | disclosed |