Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28528444 | 0.91 | CYP3A4 (0.46) | CHRM5ENPP2ATXN2TP53CYP3A4 | |
| SCHEMBL28991519 | 0.85 | SCN9A (0.42) | ENPP2ATXN2 | |
| SCHEMBL19614449 | 0.79 | — | — | |
| SCHEMBL19614469 | 0.79 | — | — | |
| SCHEMBL19614451 | 0.79 | — | — | |
| SCHEMBL28528281 | 0.78 | HRH3 (0.41) | — | |
| SCHEMBL28528446 | 0.78 | CHRM5 (0.42) | CHRM5ENPP2ATXN2TP53CYP3A4 | |
| SCHEMBL28528445 | 0.78 | CHRM5 (0.42) | CHRM5ENPP2ATXN2TP53CYP3A4 | |
| SCHEMBL28991600 | 0.77 | EPHX2 (0.42) | — | |
| SCHEMBL28526992 | 0.76 | HCRTR1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174869-A | Preparation method and medicinal application of N-phenylacetyl-2-hydroxymethyl pyrrolidine-2-formamide | 蔡霈 | 2021-01-05 | — | — | CN | disclosed |