Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28528445 | 1.00 | CHRM5 (0.42) | CHRM5CHRM2CHRM1SCN9ATP53 | |
| SCHEMBL28522822 | 0.78 | CHRM5 (0.43) | CHRM5TP53CYP3A4CYP2C9TSHR | |
| SCHEMBL28545922 | 0.77 | SMN1; SMN2 (0.38) | CYP2C19SMN1; SMN2FAAH | |
| SCHEMBL28523651 | 0.76 | KCNH2 (0.43) | HRH3 | |
| SCHEMBL28523650 | 0.76 | KCNH2 (0.43) | HRH3 | |
| SCHEMBL28528444 | 0.75 | CYP3A4 (0.46) | CHRM5TP53CYP3A4CYP2C9TSHR | |
| SCHEMBL28907976 | 0.75 | SMN1; SMN2 (0.42) | SMN1; SMN2 | |
| SCHEMBL28907975 | 0.75 | SMN1; SMN2 (0.42) | SMN1; SMN2 | |
| SCHEMBL28991793 | 0.73 | TACR1 (0.42) | CHRM2CHRM1TSHR | |
| SCHEMBL20831002 | 0.66 | KMT2A (0.67) | TP53SMN1; SMN2TDP1FAAHEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174869-A | Preparation method and medicinal application of N-phenylacetyl-2-hydroxymethyl pyrrolidine-2-formamide | 蔡霈 | 2021-01-05 | — | — | CN | disclosed |