SCHEMBL28523262

SCHEMBL28523262

O=C(O)c1cc(C(=O)O)cc(C(=O)O)c1.O=C(O)c1ccc(C(=O)OC(=O)c2cccc(C(=O)OC(=O)c3ccc(C(=O)O)cc3)c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
DAO P14920 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
SRD5A2 P31213 2/20 0.48
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
TP53 P04637 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.47
PKM P14618 1/20 0.47
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA6 P23280 1/20 0.45
CA9 Q16790 1/20 0.45
F2 P00734 1/20 0.45
LMNA P02545 1/20 0.45
AKR1C3 P42330 1/20 0.44
ATM Q13315 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1138393 0.98 TSHR (0.52) TSHRMEN1KMT2ADAONAPRT
SCHEMBL27527167 0.96 TSHR (0.50) TSHRMEN1KMT2ADAONAPRT
SCHEMBL4632174 0.94 CA12 (0.52) TSHRMEN1KMT2ADAONAPRT
SCHEMBL27504 0.90 CA12 (0.56) TSHRKMT2ADAONAPRTTP53
Isophthalic Acid SCHEMBL20500517 0.90 CA12 (0.56) TSHRKMT2ADAONAPRTTP53
SCHEMBL5689369 0.90 CA12 (0.56) TSHRKMT2ADAONAPRTTP53
Isophthalic Acid SCHEMBL5689366 0.90 CA12 (0.56) TSHRKMT2ADAONAPRTTP53
SCHEMBL16175298 0.89 TSHR (0.48) TSHRMEN1KMT2ADAONAPRT
SCHEMBL28820072 0.89 TSHR (0.60) TSHRMEN1KMT2ATP53L3MBTL1
SCHEMBL7929396 0.89 KMO (0.53) CA12CA1CA2CA6CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112403473-B Synthesis method for preparing reforming catalyst through MOFs 上海簇睿低碳能源技术有限公司 2022-12-30 CN disclosed
CN-112403473-A Synthetic method for preparing reforming catalyst through MOFs 上海簇睿低碳能源技术有限公司 2021-02-26 CN disclosed