Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21858751 | 0.85 | MAPT (0.55) | MAPTLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL28523656 | 0.84 | MAPT (0.47) | MAPTLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL21611475 | 0.83 | MAPT (0.56) | MAPTLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL21611534 | 0.83 | MAPT (0.56) | MAPTLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL21611440 | 0.82 | MAPT (0.52) | MAPTLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL9165003 | 0.81 | CA1 (0.49) | MAPTLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL21611540 | 0.81 | MAPT (0.49) | MAPTLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL21611484 | 0.81 | MAPT (0.53) | MAPTLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL23646428 | 0.80 | MAPT (0.53) | MAPTLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL21611389 | 0.80 | MAPT (0.58) | MAPTLMNAALDH1A1SMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112368276-A | Amino-pyrimidinone derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2021-02-12 | — | — | CN | disclosed |