Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5496736 | 0.85 | MAPT (0.44) | MAPTLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL28523668 | 0.84 | MAPT (0.52) | MAPTLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL21858751 | 0.84 | MAPT (0.55) | MAPTLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL21611500 | 0.80 | MAPT (0.60) | MAPTLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL21611504 | 0.78 | LMNA (0.50) | MAPTLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL21611550 | 0.78 | MAPT (0.75) | MAPTLMNAALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL21611402 | 0.77 | MAPT (0.56) | MAPTLMNAALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL21611426 | 0.77 | MAPT (0.56) | MAPTLMNAALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL21611536 | 0.77 | MAPT (0.56) | MAPTLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL28517393 | 0.77 | TRPA1 (0.36) | MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112368276-A | Amino-pyrimidinone derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2021-02-12 | — | — | CN | disclosed |