Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | NPY1R | P25929 | 1/20 | 0.58 |
| ▸ | NPY2R | P49146 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | CTSV | O60911 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | FASN | P49327 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250386 | 0.88 | ALDH1A1 (0.56) | MEN1KMT2APOLBALDH1A1PKM | |
| SCHEMBL5327852 | 0.86 | ALDH1A1 (0.68) | MEN1KMT2APOLBALDH1A1PKM | |
| SCHEMBL6184844 | 0.86 | ALDH1A1 (0.53) | MEN1KMT2APOLBALDH1A1PKM | |
| SCHEMBL9690594 | 0.84 | MAPT (0.52) | MEN1KMT2APOLBALDH1A1PKM | |
| SCHEMBL6186570 | 0.84 | ALDH1A1 (0.51) | MEN1KMT2APOLBALDH1A1PKM | |
| SCHEMBL28362604 | 0.83 | POLB (0.59) | MEN1KMT2APOLBALDH1A1PKM | |
| SCHEMBL8792969 | 0.83 | KMT2A (0.60) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL6186801 | 0.82 | ALDH1A1 (0.51) | MEN1KMT2APOLBALDH1A1PKM | |
| SCHEMBL10915060 | 0.80 | ALDH1A1 (0.63) | MEN1KMT2APOLBALDH1A1PKM | |
| SCHEMBL6634172 | 0.80 | MAPT (0.56) | MEN1KMT2APOLBALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109265386-B | Novel method for synthesizing 3-acylated indole derivative through C-H activation | 四川大学 | 2021-02-09 | — | — | CN | disclosed |