Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.36 |
| ▸ | TYMP | P19971 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27629365 | 0.78 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL11325593 | 0.72 | ALDH1A1 (0.41) | ALDH1A1KCNH2MEN1KMT2AMAPK1 | |
| SCHEMBL17008157 | 0.68 | TSHR (0.57) | ALDH1A1KCNH2TYMPMEN1KMT2A | |
| SCHEMBL5586984 | 0.68 | ESR1 (0.38) | ALDH1A1KCNH2 | |
| SCHEMBL5586702 | 0.68 | ESR1 (0.38) | ALDH1A1KCNH2 | |
| SCHEMBL18325070 | 0.68 | TSHR (0.42) | ALDH1A1KCNH2GPR35TYMP | |
| SCHEMBL9994207 | 0.68 | TSHR (0.42) | ALDH1A1KCNH2GPR35TYMP | |
| SCHEMBL13337265 | 0.68 | TSHR (0.42) | ALDH1A1KCNH2GPR35TYMP | |
| SCHEMBL28238159 | 0.67 | ALDH1A1 (0.41) | ALDH1A1KCNH2TYMPMEN1KMT2A | |
| Octane SCHEMBL8655397 | 0.66 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106966922-B | Synthesis method of functional substituted dicyanoethylene compound | 中国科学院大学 | 2020-10-27 | — | — | CN | disclosed |