SCHEMBL28524344

SCHEMBL28524344

CCCCCCc1cnc2ccccc2n1

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 6/20 0.67
KCNH2 Q12809 1/20 0.55
MAPT P10636 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
TLR7 Q9NYK1 2/20 0.48
KDM4E B2RXH2 1/20 0.48
NPC1 O15118 1/20 0.48
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
HIF1A Q16665 1/20 0.44
TLR8 Q9NR97 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28236355 1.00 PDE10A (0.67) PDE10AKCNH2MAPTMEN1KMT2A
SCHEMBL28001709 1.00 PDE10A (0.67) PDE10AKCNH2MAPTMEN1KMT2A
SCHEMBL14795853 1.00 PDE10A (0.67) PDE10AKCNH2MAPTMEN1KMT2A
SCHEMBL27964546 1.00 PDE10A (0.67) PDE10AKCNH2MAPTMEN1KMT2A
SCHEMBL28001999 1.00 PDE10A (0.67) PDE10AKCNH2MAPTMEN1KMT2A
SCHEMBL28236348 1.00 PDE10A (0.67) PDE10AKCNH2MAPTMEN1KMT2A
SCHEMBL7109686 0.98 PDE10A (0.69) PDE10AKCNH2MAPTMEN1KMT2A
SCHEMBL7068584 0.93 PDE10A (0.71) PDE10AKCNH2MAPTMEN1KMT2A
SCHEMBL9971272 0.85 PDE10A (0.77) PDE10AMAPTMEN1KMT2AKDM4E
SCHEMBL28767253 0.82 PDE10A (0.53) PDE10AKCNH2MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108043442-B Carbon-supported ruthenium nano material, preparation method thereof and application of carbon-supported ruthenium nano material in catalyzing reaction of alcohol and aromatic diamine 苏州大学 2021-03-19 CN disclosed