Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14795853 | 0.98 | PDE10A (0.67) | PDE10AKCNH2MAPTMEN1KMT2A | |
| SCHEMBL27964546 | 0.98 | PDE10A (0.67) | PDE10AKCNH2MAPTMEN1KMT2A | |
| SCHEMBL28236348 | 0.98 | PDE10A (0.67) | PDE10AKCNH2MAPTMEN1KMT2A | |
| SCHEMBL28001709 | 0.98 | PDE10A (0.67) | PDE10AKCNH2MAPTMEN1KMT2A | |
| SCHEMBL28524344 | 0.98 | PDE10A (0.67) | PDE10AKCNH2MAPTMEN1KMT2A | |
| SCHEMBL28001999 | 0.98 | PDE10A (0.67) | PDE10AKCNH2MAPTMEN1KMT2A | |
| SCHEMBL28236355 | 0.98 | PDE10A (0.67) | PDE10AKCNH2MAPTMEN1KMT2A | |
| SCHEMBL7068584 | 0.95 | PDE10A (0.71) | PDE10AKCNH2MAPTMEN1KMT2A | |
| SCHEMBL9971272 | 0.87 | PDE10A (0.77) | PDE10AMAPTMEN1KMT2AKDM4E | |
| SCHEMBL12066225 | 0.82 | PDE10A (1.00) | PDE10AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114524773-B | Synthesis method of aryl quinoxaline compound promoted by mechanical force | 浙江工业大学 | 2024-05-28 | — | — | CN | claimed |
| CN-114524773-A | Method for synthesizing aryl quinoxaline compound promoted by mechanical force | 浙江工业大学 | 2022-05-24 | — | — | CN | claimed |
| WO-2012122605-A1 | IRIDIUM BASED COMPLEX FOR WATER SPLITTING | THE UNIVERSITY OF QUEENSLAND (AU) | 2012-09-20 | — | — | WO | claimed |
| CN-102617833-A | Quinoxaline porphyrin unit based conjugated polymer as well as preparation method and application thereof | UNIV BEIJING CHEMICAL | 2012-08-01 | — | — | CN | claimed |
| US-4304898-A | HEAT RESIST METAL WIRE COATINGS | INSTITUT FRANCAIS DU PETROLE (FR) | 1981-12-08 | — | — | US | claimed |
| CN-114524773-B | Synthesis method of aryl quinoxaline compound promoted by mechanical force | 浙江工业大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-114524773-B | Synthesis method of aryl quinoxaline compound promoted by mechanical force | 浙江工业大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-114524773-B | Synthesis method of aryl quinoxaline compound promoted by mechanical force | 浙江工业大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-114524773-A | Method for synthesizing aryl quinoxaline compound promoted by mechanical force | 浙江工业大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-114524773-A | Method for synthesizing aryl quinoxaline compound promoted by mechanical force | 浙江工业大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-114524773-A | Method for synthesizing aryl quinoxaline compound promoted by mechanical force | 浙江工业大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-110423255-B | Deep red light electrophosphorescent material based on monoaryl substituted quinoxaline cyclometalated iridium (III) complex and application thereof | 常州大学 | 2022-03-01 | — | — | CN | disclosed |
| US-20030149038-A1 | Alpha-helix mimicry by a class of organic molecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-08-07 | — | — | US | disclosed |
| WO-2003040402-A2 | ALPHA-HELIX MIMICRY BY A CLASS OF ORGANIC MOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-05-15 | — | — | WO | disclosed |
| EP-0860433-B1 | QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KIRIN BREWERY (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-6143764-A | ETHER DERIVATIVES OF QUINOLINE, ANTITUMOR AGENTS | KIRIN BEER KABUSHIKI KAISHA (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0860433-A1 | QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 1998-08-26 | — | — | EP | disclosed |
| US-4304898-A | HEAT RESIST METAL WIRE COATINGS | INSTITUT FRANCAIS DU PETROLE (FR) | 1981-12-08 | — | — | US | disclosed |
| US-4304898-A | HEAT RESIST METAL WIRE COATINGS | INSTITUT FRANCAIS DU PETROLE (FR) | 1981-12-08 | — | — | US | disclosed |
| US-4304898-A | HEAT RESIST METAL WIRE COATINGS | INSTITUT FRANCAIS DU PETROLE (FR) | 1981-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149038-A1 | Alpha-helix mimicry by a class of organic molecules | SERPINH1, FABP1, HSPH1 | PDE10A 3385/4885KCNH2 3448/4885MAPT 798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.