Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 7/20 | 0.56 |
| ▸ | THRB | P10828 | 7/20 | 0.56 |
| ▸ | RARB | P10826 | 2/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | TACR2 | P21452 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27892537 | 1.00 | THRA (0.56) | THRATHRBRARBPLK1CA1 | |
| SCHEMBL22375068 | 0.85 | THRA (0.53) | THRATHRBRARBPLK1CA1 | |
| SCHEMBL18905452 | 0.82 | HSD17B10 (0.41) | THRATHRBRARBPLK1MEN1 | |
| SCHEMBL27887440 | 0.82 | THRA (0.54) | THRATHRBRARBPLK1MEN1 | |
| SCHEMBL15177389 | 0.82 | THRA (0.58) | THRATHRBRARBPLK1MEN1 | |
| SCHEMBL10938918 | 0.81 | RARB (0.58) | THRATHRBRARBPLK1CA1 | |
| SCHEMBL11570191 | 0.80 | RARB (0.58) | THRATHRBRARBPLK1ALDH1A1 | |
| SCHEMBL8732968 | 0.80 | ESR1 (0.50) | THRATHRBRARBPLK1CA1 | |
| SCHEMBL8732972 | 0.80 | ESR1 (0.50) | THRATHRBRARBPLK1CA1 | |
| SCHEMBL8729056 | 0.80 | ESR1 (0.50) | THRATHRBRARBPLK1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112299946-A | Method for synthesizing 1, 2-disubstituted olefin by reacting terminal group olefin with sulfoxide | 沅江华龙催化科技有限公司 | 2021-02-02 | — | — | CN | disclosed |