Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21589614 | 0.93 | SLC10A2 (0.34) | KDM4EMEN1ALDH1A1MAPTRAB9A | |
| SCHEMBL29462791 | 0.93 | SLC10A2 (0.34) | KDM4EMEN1ALDH1A1MAPTRAB9A | |
| SCHEMBL21585977 | 0.91 | NR1H4 (0.32) | KDM4EALDH1A1 | |
| SCHEMBL28535317 | 0.89 | SLC10A2 (0.30) | — | |
| SCHEMBL28529191 | 0.87 | SLC10A2 (0.31) | — | |
| SCHEMBL23375134 | 0.86 | DDB1 (0.35) | KDM4EMEN1ALDH1A1MAPTRAB9A | |
| SCHEMBL28533803 | 0.85 | SLC10A2 (0.31) | — | |
| SCHEMBL28536821 | 0.85 | SLC10A2 (0.32) | KMT2A | |
| SCHEMBL21589617 | 0.85 | — | — | |
| SCHEMBL21585976 | 0.83 | NR1H4 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112449637-B | Benzothiazepine compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-112449637-A | Benzothia (di) azepanes and their use as bile acid modulators | 阿尔比里奥公司 | 2021-03-05 | — | — | CN | disclosed |