SCHEMBL28524666

SCHEMBL28524666

N[C@@H]1CCC[C@@H]1C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2293002 0.94 THRB (0.47) THRBMEN1KMT2A
SCHEMBL16821927 0.94 THRB (0.47) THRBMEN1KMT2A
Hydrochloric Acid SCHEMBL6268171 0.92 THRB (0.45) THRBMEN1KMT2A
Hydrochloric Acid SCHEMBL2102258 0.92 THRB (0.45) THRBMEN1KMT2A
SCHEMBL28937241 0.84 THRB (0.36) THRBMEN1KMT2A
Hydrochloric Acid SCHEMBL31423955 0.80
Hydrochloric Acid SCHEMBL18669715 0.80
Hydrochloric Acid SCHEMBL30398995 0.80
SCHEMBL6114089 0.78
SCHEMBL30774549 0.72 THRB (0.40) THRBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112279774-B Dibromobenzyl derivative, stereoisomer or salt thereof, preparation method and application 成都施贝康生物医药科技有限公司 2023-05-30 CN disclosed
CN-112279774-A Dibromo benzyl derivative, stereoisomer or salt thereof, preparation method and application 成都施贝康生物医药科技有限公司 2021-01-29 CN disclosed