Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 18/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21491972 | 0.78 | HCRTR1 (0.44) | HCRTR1CCNKCDK12 | |
| SCHEMBL30744401 | 0.78 | HCRTR1 (0.44) | HCRTR1CCNKCDK12 | |
| SCHEMBL21491975 | 0.78 | HCRTR1 (0.44) | HCRTR1CCNKCDK12 | |
| SCHEMBL21492759 | 0.77 | HCRTR1 (0.48) | HCRTR1CCNKCDK12HCRTR2 | |
| Hydrochloric Acid SCHEMBL21491930 | 0.76 | HCRTR1 (0.43) | HCRTR1CCNKCDK12 | |
| Hydrochloric Acid SCHEMBL30744328 | 0.76 | HCRTR1 (0.43) | HCRTR1CCNKCDK12 | |
| Hydrochloric Acid SCHEMBL21491928 | 0.76 | HCRTR1 (0.43) | HCRTR1CCNKCDK12 | |
| SCHEMBL30744422 | 0.74 | HCRTR1 (0.45) | HCRTR1CCNKCDK12 | |
| SCHEMBL21503414 | 0.74 | HCRTR1 (0.45) | HCRTR1CCNKCDK12 | |
| SCHEMBL26693505 | 0.74 | HCRTR1 (0.45) | HCRTR1CCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218865-B | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-112218865-A | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2021-01-12 | — | — | CN | disclosed |