Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL911130 | 0.88 | — | — | |
| Methyl Alcohol SCHEMBL10751983 | 0.78 | — | — | |
| Isobutanol SCHEMBL5921907 | 0.76 | TSHR (0.47) | KDM4EPOLBCHRM1OPRM1OPRL1 | |
| SCHEMBL775624 | 0.74 | — | — | |
| Propionic Acid SCHEMBL9223501 | 0.74 | KDM4E (0.50) | KDM4EPOLBCHRM1SMN1; SMN2OPRM1 | |
| Propionic Acid SCHEMBL11080011 | 0.72 | KDM4E (0.49) | KDM4EPOLBCHRM1SMN1; SMN2OPRM1 | |
| SCHEMBL23269644 | 0.69 | L3MBTL1 (0.40) | KDM4ESMN1; SMN2OPRM1OPRL1ALDH1A1 | |
| Propanol SCHEMBL2745949 | 0.69 | — | — | |
| Acetic Acid SCHEMBL9219154 | 0.69 | KDM4E (0.46) | KDM4EPOLBCHRM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24454166 | 0.68 | KMT2A (0.46) | KDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794899-A | Novel heterocyclic compounds, compositions, methods of preparation and uses thereof | 欧加农研发芬兰有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-112390852-B | Compound as protein degradation agent and preparation method and application thereof | 上海济煜医药科技有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-112390852-A | Compound as protein degradation agent and preparation method and application thereof | 上海济煜医药科技有限公司 | 2021-02-23 | — | — | CN | disclosed |