Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2880891 | 0.96 | CNR1 (0.54) | CNR1MAPTNPSR1NPC1RAB9A | |
| SCHEMBL2857734 | 0.91 | CNR1 (0.49) | CNR1MAPTNPSR1NPC1RAB9A | |
| SCHEMBL2856146 | 0.91 | CNR1 (0.53) | CNR1MAPTNPSR1NPC1RAB9A | |
| SCHEMBL2855846 | 0.85 | CNR1 (0.55) | CNR1MAPTTP53NPSR1NPC1 | |
| SCHEMBL2854327 | 0.84 | CNR1 (0.58) | CNR1MAPTNPSR1NPC1RAB9A | |
| SCHEMBL2860983 | 0.82 | MAPT (0.49) | MAPTP2RX7NPSR1NPC1RAB9A | |
| SCHEMBL2858063 | 0.82 | MAPT (0.57) | MAPTP2RX7NPSR1NPC1RAB9A | |
| SCHEMBL2862263 | 0.82 | MAPT (0.47) | CNR1MAPTP2RX7NPSR1NPC1 | |
| SCHEMBL2852316 | 0.82 | NPC1 (0.47) | CNR1MAPTNPSR1NPC1RAB9A | |
| SCHEMBL2855610 | 0.82 | CNR1 (0.58) | CNR1MAPTNPSR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |