Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856146 | 0.94 | CNR1 (0.53) | CNR1LMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL2880891 | 0.89 | CNR1 (0.54) | CNR1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2853232 | 0.88 | CCR1 (0.48) | ALDH1A1SMN1; SMN2KMT2AMEN1RAB9A | |
| SCHEMBL2860983 | 0.86 | MAPT (0.49) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2852504 | 0.85 | CNR1 (0.56) | CNR1LMNATP53RAB9ANPC1 | |
| SCHEMBL2857734 | 0.84 | CNR1 (0.49) | CNR1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2854327 | 0.83 | CNR1 (0.58) | CNR1ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2855610 | 0.83 | CNR1 (0.58) | CNR1SMN1; SMN2KMT2AHTTRAB9A | |
| SCHEMBL2858063 | 0.82 | MAPT (0.57) | LMNAALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2852086 | 0.82 | ITGB3 (0.53) | LMNAALDH1A1RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |