Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.59 |
| ▸ | GRM2 | Q14416 | 10/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29809435 | 1.00 | TNF (0.59) | TNFGRM2KDM4EHTTACHE | |
| SCHEMBL29809443 | 0.90 | TNF (0.64) | TNFGRM2KDM4EHTTACHE | |
| SCHEMBL4552574 | 0.88 | TNF (0.63) | TNFKDM4EHTTACHEPSMB1 | |
| SCHEMBL28525351 | 0.87 | TNF (0.61) | TNFKDM4EHTTACHETDP1 | |
| SCHEMBL29809320 | 0.85 | TNF (0.55) | TNFKDM4EACHEPSMB1PSMB5 | |
| SCHEMBL179072 | 0.85 | TNF (0.55) | TNFKDM4EACHEPSMB1PSMB5 | |
| SCHEMBL1238170 | 0.82 | TNF (0.52) | TNFKDM4EHTTACHEPSMB1 | |
| SCHEMBL13046538 | 0.82 | TNF (0.56) | TNFKDM4EHTTACHEPSMB1 | |
| SCHEMBL9690276 | 0.81 | TNF (0.52) | TNFKDM4EHTTACHEPSMB1 | |
| SCHEMBL28189599 | 0.79 | HSP90AB1 (0.59) | TNFGRM2KDM4EACHEPSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981799-B | Method for synthesizing quinolinone compound or isomers thereof | 天津理工大学 | 2021-02-19 | — | — | CN | claimed |