SCHEMBL28525265

CC(C)C[C@H](NC(=O)[C@@H](O)[C@@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)N[C@H](Cc1ccccc1)[C@H](O)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	REN	P00797	7/20	0.59

▸	PSEN1	P49768	12/20	0.58

▸	PSEN2	P49810	12/20	0.58

▸	APH1B	Q8WW43	12/20	0.58

▸	NCSTN	Q92542	12/20	0.58

▸	APH1A	Q96BI3	12/20	0.58

▸	PSENEN	Q9NZ42	12/20	0.58

▸	APP	P05067	1/20	0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL28525267	1.00	REN (0.59)	RENPSEN1PSEN2APH1BNCSTN
SCHEMBL28525268	1.00	REN (0.59)	RENPSEN1PSEN2APH1BNCSTN
SCHEMBL23302438	0.93	PSEN1 (0.61)	RENPSEN1PSEN2APH1BNCSTN
SCHEMBL11095014	0.93	PSEN1 (0.61)	RENPSEN1PSEN2APH1BNCSTN
SCHEMBL14725527	0.93	PSEN1 (0.61)	RENPSEN1PSEN2APH1BNCSTN
SCHEMBL27041288	0.93	PSEN1 (0.61)	RENPSEN1PSEN2APH1BNCSTN
SCHEMBL11089707	0.89	PSEN1 (0.61)	RENPSEN1PSEN2APH1BNCSTN
SCHEMBL22393402	0.89	PSEN1 (0.67)	RENPSEN1PSEN2APH1BNCSTN
SCHEMBL21012316	0.89	REN (0.60)	RENPSEN1PSEN2APH1BNCSTN
SCHEMBL17899496	0.88	PSEN1 (0.63)	RENPSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-112125951-A	Impurities in ubenimex bulk drug and preparation method thereof	深圳万乐药业有限公司	2020-12-25	—	—	CN	disclosed