Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 19/20 | 0.65 |
| ▸ | THRB | P10828 | 19/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.65 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29497540 | 1.00 | THRA (0.65) | THRATHRBCYP2C9CYP2C8UGT1A1 | |
| SCHEMBL27166006 | 0.88 | THRA (0.63) | THRATHRBCYP2C9CYP2C8UGT1A1 | |
| SCHEMBL27166008 | 0.87 | THRA (0.78) | THRATHRBCYP2C9CYP2C8UGT1A1 | |
| SCHEMBL30046150 | 0.87 | THRA (0.78) | THRATHRBCYP2C9CYP2C8UGT1A1 | |
| SCHEMBL30045292 | 0.87 | THRA (0.66) | THRATHRBCYP2C9CYP2C8UGT1A1 | |
| SCHEMBL27166009 | 0.87 | THRA (0.66) | THRATHRBCYP2C9CYP2C8UGT1A1 | |
| SCHEMBL23022537 | 0.86 | THRA (0.88) | THRATHRBCYP2C9CYP2C8UGT1A1 | |
| SCHEMBL24032546 | 0.83 | THRA (0.62) | THRATHRBCYP2C9CYP2C8UGT1A1 | |
| SCHEMBL28745831 | 0.81 | THRA (0.76) | THRATHRBCYP2C9CYP2C8UGT1A1 | |
| Resmetirom SCHEMBL22551618 | 0.80 | THRA (0.88) | THRATHRBCYP2C9CYP2C8UGT1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409340-B | Halogen substituted phenyl ether compound and application thereof | 海创药业股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-112409340-A | Halogen substituted phenyl ether compound and application thereof | 海创药业股份有限公司 | 2021-02-26 | — | — | CN | disclosed |