Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 4/20 | 0.57 |
| ▸ | PIM1 | P11309 | 4/20 | 0.57 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 3/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29018404 | 1.00 | AKR1B1 (0.57) | AKR1B1PIM1PIM2NPC1RAB9A | |
| SCHEMBL6036473 | 1.00 | AKR1B1 (0.57) | AKR1B1PIM1PIM2NPC1RAB9A | |
| SCHEMBL6036475 | 1.00 | AKR1B1 (0.57) | AKR1B1PIM1PIM2NPC1RAB9A | |
| SCHEMBL3793560 | 0.91 | PPARG (0.62) | AKR1B1PIM1PIM2NPC1RAB9A | |
| SCHEMBL13347260 | 0.91 | PPARG (0.62) | AKR1B1PIM1PIM2NPC1RAB9A | |
| SCHEMBL3802111 | 0.91 | PPARG (0.62) | AKR1B1PIM1PIM2NPC1RAB9A | |
| SCHEMBL3793562 | 0.91 | PPARG (0.62) | AKR1B1PIM1PIM2NPC1RAB9A | |
| SCHEMBL13347261 | 0.91 | PPARG (0.62) | AKR1B1PIM1PIM2NPC1RAB9A | |
| SCHEMBL5058932 | 0.91 | PPARG (0.62) | AKR1B1PIM1PIM2NPC1RAB9A | |
| SCHEMBL3797293 | 0.88 | HPGD (0.56) | AKR1B1PIM1PIM2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112209896-B | Thiazolidinedione derivatives and pharmaceutical compositions containing the same | 苏州泽璟生物制药股份有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-112209896-A | Thiazolidinedione derivatives and pharmaceutical compositions containing the same | 苏州泽璟生物制药股份有限公司 | 2021-01-12 | — | — | CN | disclosed |