Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27851405 | 0.83 | KDM4E (0.51) | KDM4ERAB9ANPC1MEN1KMT2A | |
| SCHEMBL17674285 | 0.82 | KDM4E (0.45) | KDM4ERAB9ANPC1MEN1KMT2A | |
| SCHEMBL29855946 | 0.82 | KDM4E (0.45) | KDM4ERAB9ANPC1MEN1KMT2A | |
| SCHEMBL27697913 | 0.81 | GAA (0.35) | KDM4ERAB9ANPC1MEN1KMT2A | |
| SCHEMBL27603373 | 0.81 | CCNE1 (0.37) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27841724 | 0.80 | ACACB (0.34) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL27796858 | 0.79 | CCNE1 (0.37) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL176060 | 0.78 | LOXL2 (0.37) | KDM4ERAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL28579573 | 0.78 | GAA (0.36) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27911742 | 0.78 | ACACB (0.40) | HSD11B1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384517-A | Heteroaryl compounds and uses thereof | 新旭生技股份有限公司 | 2021-02-19 | — | — | CN | disclosed |