Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30854865 | 0.90 | — | — | |
| SCHEMBL30854866 | 0.90 | — | — | |
| SCHEMBL152391 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL13279830 | 0.88 | ALDH1A1 (0.34) | ALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL16738326 | 0.80 | — | — | |
| SCHEMBL30891 | 0.78 | — | — | |
| SCHEMBL21869866 | 0.75 | — | — | |
| SCHEMBL16145218 | 0.72 | NPC1 (0.33) | HTTSMN1; SMN2 | |
| SCHEMBL13243508 | 0.70 | — | — | |
| SCHEMBL16377751 | 0.69 | ERN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538072-B | Aminopyrimidine EGFR inhibitors | 齐鲁制药有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-112538072-A | Novel aminopyrimidine EGFR (epidermal growth factor receptor) inhibitor | 齐鲁制药有限公司 | 2021-03-23 | — | — | CN | disclosed |