Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 6/20 | 0.52 |
| ▸ | CCND1 | P24385 | 6/20 | 0.52 |
| ▸ | CCND2 | P30279 | 6/20 | 0.52 |
| ▸ | CCND3 | P30281 | 6/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | LDHB | P07195 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 3/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28525903 | 1.00 | CDK4 (0.52) | CDK4CCND1CCND2CCND3MAPK8 | |
| SCHEMBL23141677 | 0.89 | CDK4 (0.47) | CDK4CCND1CCND2CCND3MAPK8 | |
| SCHEMBL23141676 | 0.89 | CDK4 (0.47) | CDK4CCND1CCND2CCND3MAPK8 | |
| SCHEMBL28537531 | 0.86 | CDK4 (0.69) | CDK4CCND1CCND2CCND3MAPK8 | |
| SCHEMBL28537530 | 0.86 | CDK4 (0.69) | CDK4CCND1CCND2CCND3MAPK8 | |
| SCHEMBL28909366 | 0.82 | CDK4 (0.58) | CDK4CCND1CCND2CCND3MAPK8 | |
| SCHEMBL28909368 | 0.82 | CDK4 (0.58) | CDK4CCND1CCND2CCND3MAPK8 | |
| SCHEMBL5265689 | 0.81 | CDK4 (0.68) | CDK4CCND1CCND2CCND3MAPK8 | |
| SCHEMBL23141494 | 0.79 | CDK4 (0.49) | CDK4CCND1CCND2CCND3MAPK8 | |
| SCHEMBL23141496 | 0.79 | CDK4 (0.49) | CDK4CCND1CCND2CCND3MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469719-A | Heterocondensed pyridone compounds and their use as IDH inhibitors | 内尔维亚诺医疗科学公司 | 2021-03-09 | — | — | CN | claimed |
| CN-112469719-A | Heterocondensed pyridone compounds and their use as IDH inhibitors | 内尔维亚诺医疗科学公司 | 2021-03-09 | — | — | CN | disclosed |