Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 18/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21616619 | 1.00 | RORC (0.44) | RORCUTS2RPDE2A | |
| SCHEMBL21619980 | 0.95 | RORC (0.44) | RORCUTS2RPDE2A | |
| SCHEMBL21619984 | 0.94 | RORC (0.44) | RORCUTS2RPDE2A | |
| SCHEMBL21616635 | 0.93 | RORC (0.44) | RORCUTS2RPDE2A | |
| SCHEMBL21616653 | 0.92 | RORC (0.44) | RORCUTS2RPDE2A | |
| SCHEMBL28532532 | 0.92 | RORC (0.44) | RORCUTS2RPDE2A | |
| SCHEMBL21619888 | 0.91 | RORC (0.46) | RORCPDE2A | |
| SCHEMBL21619986 | 0.90 | RORC (0.43) | RORCUTS2RPDE2A | |
| SCHEMBL21619882 | 0.90 | RORC (0.47) | RORCPDE2A | |
| SCHEMBL21619662 | 0.88 | RORC (0.42) | RORCUTS2RPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | disclosed |