Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28539917 | 0.90 | EGFR (0.59) | EGFR | |
| SCHEMBL23441739 | 0.87 | EGFR (0.65) | EGFR | |
| SCHEMBL23441755 | 0.86 | EGFR (0.80) | EGFR | |
| SCHEMBL23441736 | 0.85 | EGFR (0.80) | EGFR | |
| SCHEMBL29208847 | 0.84 | EGFR (0.51) | EGFR | |
| SCHEMBL28836702 | 0.82 | EGFR (0.48) | EGFR | |
| SCHEMBL23441752 | 0.80 | EGFR (0.64) | EGFR | |
| SCHEMBL23441741 | 0.80 | EGFR (0.64) | EGFR | |
| SCHEMBL25001408 | 0.80 | EGFR (0.64) | EGFR | |
| SCHEMBL29877050 | 0.80 | EGFR (0.64) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538072-B | Aminopyrimidine EGFR inhibitors | 齐鲁制药有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-112538072-A | Novel aminopyrimidine EGFR (epidermal growth factor receptor) inhibitor | 齐鲁制药有限公司 | 2021-03-23 | — | — | CN | disclosed |