Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.51 |
| ▸ | BTK | Q06187 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28836702 | 0.92 | EGFR (0.48) | EGFRBTK | |
| SCHEMBL25001948 | 0.88 | EGFR (0.64) | EGFRBTK | |
| SCHEMBL28535528 | 0.86 | EGFR (0.61) | EGFRBTK | |
| SCHEMBL29208869 | 0.86 | EGFR (0.44) | EGFRBTK | |
| SCHEMBL25821590 | 0.85 | EGFR (0.56) | EGFR | |
| SCHEMBL28539917 | 0.84 | EGFR (0.59) | EGFR | |
| SCHEMBL28526204 | 0.84 | EGFR (0.60) | EGFR | |
| SCHEMBL25001607 | 0.84 | EGFR (0.54) | EGFRBTK | |
| SCHEMBL25002438 | 0.84 | EGFR (0.56) | EGFR | |
| SCHEMBL25002439 | 0.84 | EGFR (0.54) | EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538072-B | Aminopyrimidine EGFR inhibitors | 齐鲁制药有限公司 | 2024-02-06 | — | — | CN | disclosed |