Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.51 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14266782 | 0.82 | UBE2T (0.59) | UBE2TASIC3HPGDGAACYP1A2 | |
| SCHEMBL371155 | 0.78 | UBE2T (0.63) | UBE2TASIC3HPGDGAACYP1A2 | |
| SCHEMBL14256500 | 0.76 | UBE2T (0.53) | UBE2TASIC3HPGDGAACYP1A2 | |
| SCHEMBL15999437 | 0.76 | HPGD (0.50) | UBE2TASIC3HPGDGAACYP1A2 | |
| SCHEMBL24691375 | 0.76 | UBE2T (0.56) | UBE2TASIC3HPGDGAACYP1A2 | |
| SCHEMBL620659 | 0.75 | UBE2T (0.59) | UBE2TASIC3HPGDGAACYP1A2 | |
| Dimethylformamide SCHEMBL28052319 | 0.75 | HPGD (0.49) | UBE2TASIC3HPGDGAACYP1A2 | |
| SCHEMBL13227897 | 0.74 | UBE2T (0.54) | UBE2TASIC3HPGDGAACYP1A2 | |
| SCHEMBL11207950 | 0.74 | UBE2T (0.54) | UBE2TASIC3HPGDGAACYP1A2 | |
| SCHEMBL13936940 | 0.73 | UBE2T (0.53) | UBE2TASIC3HPGDGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109020916-B | Substituted benzothiazole C2 alkylated derivative and application thereof | 浙江工业大学 | 2021-02-09 | — | — | CN | disclosed |