SCHEMBL28527348

SCHEMBL28527348

c1ccc(-c2cccc(Nc3ccc(-c4ccccc4)c(-c4ccccc4)n3)n2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.47
RAB9A P51151 4/20 0.47
KMT2A Q03164 4/20 0.47
ASIC3 Q9UHC3 1/20 0.41
CNR1 P21554 1/20 0.40
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALPG P10696 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NPC1 O15118 2/20 0.38
ATM Q13315 1/20 0.38
KARS1 Q15046 6/20 0.38
ADORA3 P0DMS8 2/20 0.38
HIF1A Q16665 1/20 0.38
TRPV3 Q8NET8 1/20 0.37
ADORA2A P29274 3/20 0.35
ADORA2B P29275 3/20 0.35
ADORA1 P30542 3/20 0.35
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14234645 0.84 MEN1 (0.65) MEN1RAB9AKMT2AASIC3CNR1
SCHEMBL14234652 0.81 MEN1 (0.60) MEN1RAB9AKMT2AASIC3CNR1
SCHEMBL834140 0.77 MEN1 (0.52) MEN1RAB9AKMT2AASIC3MAPT
SCHEMBL21390796 0.75 MAPT (0.69) MEN1RAB9AKMT2AASIC3CNR1
Biphenyl SCHEMBL27906737 0.73 RAB9A (0.56) MEN1RAB9AKMT2AMAPTKDM4E
SCHEMBL21312575 0.73 MEN1 (0.49) MEN1RAB9AKMT2AMAPTKDM4E
SCHEMBL16844614 0.72 MEN1 (0.48) MEN1RAB9AKMT2AASIC3CNR1
SCHEMBL21312021 0.71 SYK (0.53) MEN1KMT2AMAPTADORA2AADORA1
SCHEMBL24075103 0.70 RAB9A (0.55) MEN1RAB9AKMT2AASIC3CNR1
SCHEMBL20434025 0.70 CYP1A2 (0.42) MEN1RAB9AKMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108707169-B Tetradentate platinum complexes 通用显示公司 2021-02-12 CN disclosed
CN-108424427-B Tetradentate platinum complexes 通用显示公司 2021-02-09 CN disclosed