SCHEMBL28527489

SCHEMBL28527489

Nc1ccc(C(=O)c2cc(N)cc(OCc3ccccc3)c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 2/20 0.59
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
MAOB P27338 4/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
MAPT P10636 3/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
GAA P10253 2/20 0.55
RAB9A P51151 2/20 0.55
MAOA P21397 1/20 0.55
PARP10 Q53GL7 1/20 0.52
NR4A2 P43354 2/20 0.51
NR4A1 P22736 1/20 0.51
NR4A3 Q92570 1/20 0.51
ALDH1A1 P00352 3/20 0.51
HTT P42858 2/20 0.51
PTGES O14684 1/20 0.47
SMPD1 P17405 1/20 0.47
PPARG P37231 1/20 0.46
PLA2G4B P0C869 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6654887 0.87 SRD5A2 (0.77) SRD5A2MAOBSMN1; SMN2MAPTL3MBTL1
SCHEMBL7110511 0.83 MAOB (0.67) MEN1KMT2AMAOBSMN1; SMN2MAPT
SCHEMBL21483726 0.82 MEN1 (0.59) SRD5A2MEN1KMT2AMAOBSMN1; SMN2
SCHEMBL417403 0.82 KMT2A (0.59) SRD5A2MEN1KMT2AMAOBSMN1; SMN2
SCHEMBL27395760 0.81 MEN1 (0.57) SRD5A2MEN1KMT2AMAOBSMN1; SMN2
SCHEMBL5221387 0.81 LMNA (0.62) MEN1KMT2AMAOBSMN1; SMN2RAB9A
SCHEMBL14255438 0.80 SRD5A2 (0.65) SRD5A2MEN1KMT2AMAOBSMN1; SMN2
SCHEMBL3620652 0.80 MEN1 (0.60) SRD5A2MEN1KMT2AMAOBSMN1; SMN2
SCHEMBL8557631 0.80 MEN1 (0.56) SRD5A2MEN1KMT2AMAOBSMN1; SMN2
Hydrochloric Acid SCHEMBL5221379 0.80 LMNA (0.60) MEN1KMT2AMAOBSMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112512792-A Laminate and method for producing laminate 东洋纺株式会社 2021-03-16 CN disclosed