Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 5/20 | 0.56 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.56 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856551 | 0.91 | KMT2A (0.57) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2851981 | 0.89 | MAPK13 (0.54) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2861883 | 0.88 | MAPK1 (0.53) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2850856 | 0.86 | MAPK13 (0.57) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2856752 | 0.86 | MAPK13 (0.54) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2855113 | 0.85 | MAPK14 (0.71) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2861025 | 0.84 | MAPK1 (0.61) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2858700 | 0.83 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL6653318 | 0.82 | MAPK13 (0.75) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2854972 | 0.82 | MAPK14 (0.60) | MAPK13MAPK12MAPK11MAPK14KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101115728-B | Triazole substituted aminobenzophenone compounds | LEO PHARMA AS | 2012-12-19 | — | — | CN | disclosed |
| US-8293772-B2 | Triazole substituted aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2012-10-23 | — | — | US | disclosed |
| EP-1828148-B1 | TRIAZOLE SUBSTITUTED AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA AS (DK) | 2010-01-20 | — | — | EP | disclosed |
| CN-101115728-A | Triazole substituted aminobenzophenone compounds | LEO PHARMA AS (DK) | 2008-01-30 | — | — | CN | disclosed |
| US-20060128766-A1 | Triazole substituted aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128766-A1 | Triazole substituted aminobenzophenone compounds | NFKBIA, UACA, CYP1B1 | MAPK13 1436/4885MAPK12 1829/4885MAPK11 919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.