Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL29558580 | 0.93 | KDM4C (0.55) | AKR1B1KDM4CKDM4APHF8KDM2A | |
| Propane SCHEMBL1389494 | 0.93 | AKR1B1 (0.50) | AKR1B1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL29660871 | 0.93 | LMNA (0.53) | AKR1B1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL125280 | 0.93 | — | — | |
| Butane SCHEMBL3035488 | 0.91 | AKR1B1 (0.54) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL28429454 | 0.90 | KDM4C (0.50) | AKR1B1KDM4CKDM4APHF8KDM2A | |
| Hydrochloric Acid SCHEMBL5242594 | 0.90 | KDM4C (0.50) | AKR1B1KDM4CKDM4APHF8KDM2A | |
| Ammonia Solution, Strong SCHEMBL28632868 | 0.90 | KDM4C (0.50) | AKR1B1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL29231952 | 0.90 | KDM4C (0.50) | AKR1B1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL27515084 | 0.90 | KDM4C (0.50) | AKR1B1KDM4CKDM4APHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678942-B | Method for improving fertility of distant hybridization progeny of rice and protein used by method | 中国农业大学 | 2021-02-26 | — | — | CN | disclosed |
| CN-109536636-B | Molecular marker for identifying fertility of hybrid progeny of common wild rice and cultivated rice and application thereof | 中国农业大学 | 2020-11-03 | — | — | CN | disclosed |