Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 2/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19613593 | 0.86 | SCN8A (0.42) | STSMAPTBMP1MEN1KMT2A | |
| SCHEMBL19627593 | 0.81 | SCN8A (0.42) | STSMAPTBMP1MEN1KMT2A | |
| SCHEMBL19613659 | 0.78 | SCN8A (0.46) | STSBMP1PDE4APDE4BPDE4C | |
| SCHEMBL19613480 | 0.76 | SCN1A (0.42) | STSMAPTBMP1MEN1KMT2A | |
| SCHEMBL19631502 | 0.76 | SCN1A (0.42) | STSMAPTBMP1MEN1KMT2A | |
| SCHEMBL19634014 | 0.76 | SCN1A (0.42) | STSMAPTBMP1MEN1KMT2A | |
| SCHEMBL19613880 | 0.75 | SCN1A (0.41) | STSBMP1PDE4BSCN1ASCN8A | |
| SCHEMBL19633926 | 0.74 | STS (0.36) | STSMAPTMEN1KMT2APDE4A | |
| SCHEMBL19614028 | 0.74 | SCN1A (0.41) | STSBMP1SCN1ASCN8AGPR119 | |
| SCHEMBL19631557 | 0.73 | CNR1 (0.41) | STSBMP1SCN1ASCN8ADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109526219-B | Benzenesulfonamides and their use as therapeutic agents | 泽农医药公司 | 2021-03-12 | — | — | CN | disclosed |